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2011

(pdf) - Carter, A.P., Cho, C., Jin, L., Vale, R.D. (2011) Crystal structure of the dynein motor domain. Science 331: 1159-1165. (cover). PMCID: PMC21330489.
(pdf) - Huckaba, T.M., Gennerich, A., Wilhelm, J.E., Chishti, A.H. and Vale, R.D. (2011) Kinesin-73 is a processive motor that localizes to Rab5-containing organelles. J Biol Chem 286: 7457-7467. PMCID: PMC3045001.
(pdf) - Petry, S., Pugieux, C., Nedelec, F.J., Vale, R.D. (2011) Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts. Proc Natl Acad Sci 108: 14473-14478. PMCID: PMC3167534.
(pdf) - Petry, S. and Vale, R.D. (2011) A new cap for kinetochore fibre minus ends. Nat Cell Biol. Advance Online Publication.
(pdf) - Singhvi, A., Geuliere, J., Talavera, K., Cordes, S., Ou, G., Vale, R.D., Prasad, B.C., Clark, S.G. Garriga, G. (2011). The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Curr Biol 21: 948-954. PMCID in process.

2010

(pdf) - Carter, A.P. and Vale, R.D. (2010) Communication between the AAA+ ring and microtubule- binding domain of dynein. Biochem Cell Biol 88: 15-21. PMCID: PMC2894566.
(pdf) - D'Ambrosio, M.V. and Vale, R.D. (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J. Cell Biol. 191: 471-478. PMCID: PMC3003316.
(pdf) - Edelstein, A., Amodaj, N., Hoover, K., Vale, R., and Stuurman, N. (2010) Computer control of microscopes using mManager. Curr Protocols in Molec Biol Supp 92: 14.20.2-14.20.17.
(pdf) - Goodwin, S.S. and Vale, R.D. (2010) Patronin regulates the microtubule network by protecting microtubule minus ends. Cell 143: 263-274. PMCID: PMC3008421.
(pdf) - Ou, G., Stuurman, N., D'Ambrosio, M., and Vale, R.D. (2010) Polarized myosin produces unequal-size daughters during asymmetric cell division. Science 330: 677. PMID 20929735. NIHMSID #268018.
(pdf) - Tole, S., Vale, R.D. (2010) Young leaders for biology in India. Science 329: 1441.
(pdf) - Uehara, R., Goshima, G., Mabuchi, I., Vale, R.D., Spudich, J.A., Griffis, E.R. (2010). Determinants of myosin II cortical localizaion during cytokinesis. Curr. Biol. 20: 1080-1085. PMCID: PMC2930192.
(pdf) - Vale, R.D. (2010) It's a wonderful life: a career as an academic scientist. Mol Biol Cell 21: 11-14. PMCID: PMC2801704.
(pdf) - Yu, C.-H., Wu, H.-J., Kaizuka, Y., Vale, R.D., Groves, J.T. (2010) Altered actin centripetal retrograde flow in physically restricted immunological synapses. PL0S One: 5(7): e11878. PMCID: PMC2912367.
(pdf) - Yudushkin, I.A., and Vale, R.D. (2010) Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3{zeta} in the endosomal compartment. Proc Natl Acad Sci USA 107: 22128-22133. PMCID: PMC3009781.

2009

(pdf) - Depristo, M.A., Chang, L., Vale, R.D., Khan, S.M., and Lipkow, K. (2009) Introducing simulated cellular architecture to the quantitative analysis of fluorescent microscopy. Prog Biophys Mol Biol. 100: 25–32. PMID: 19628003. PMCID: PMC2805826.
(pdf) - Gennerich, A. and Vale, R. D. . (2009) Walking the walk: How kinesin and dynein coordinate their steps. Curr Opinion in Cell Biol 21: 59-67. PMID: 19179063. PMCID: PMC2668149.
(pdf) - Kaizuka, Y., Douglass, A.D., Vardhana, S., Dustin, M.L. and Vale, R.D. (2009) The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells. J Cell Biol 185: 521-34. PMID: 19398758. PMCID: PMC2700390.
(pdf) - Kardon, J.R., Reck-Peterson, S.L. and Vale, R.D. (2009) Regulation of the processivity and intracellular localization of S. cerevisiae dynein by dynactin. Proc Natl Acad Sci USA 106: 5669-74. PMID: 19293377. PMCID: PMC2657088.
(pdf) - Kardon, J.R. and Vale R.D. (2009) Regulators of the cytoplasmic dynein motor. Nature Rev Molec Cell Biol 10: 854-865. PMID: 19935668. NIHMSID 161107.
(pdf) - Ou, G. and Vale, R.D. (2009) Molecular signatures of Cell migration in C. elegans Q neuroblasts. J Cell Biol 185: 77-85. PMID: 19349580. PMCID: PMC2700521.
(pdf) - Uehara, R., Nozawa, R., Tomioka, A., Petry, S., Vale, R.D., Obuse, C. and Goshima, G. (2009) The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc Natl Acad Sci USA 106: 6998-7003. PMID: 19369198. PMCID: PMC2668966.
(pdf) - Vale R.D., Dell, K. (2009) The biological sciences in India: Aiming high for the future. J Cell Biol 184: 342-53. (cover) PMID: 19204144. PMCID: PMC2646550.
(pdf) - Vale, R. D., Spudich, J. A., and Griffis, E. (2009) Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells. J. Cell Biol. 186: 727–738. PMID: 19720876. PMCID: PMC2742194.

2008

(pdf) - Carter, A., Garbarino, J.E., Wilson-Kubalek, E.M., Shipley, W.E., Cho, C., Milligan, R.A., Vale, R.D., Gibbons, I.R. (2008)Structure and functional role of dynein's microtubule binding domain. Science 322: 1691-1695. (Supplemental) PMID: 19074350. PMCID: PMC2663340.
(pdf) - Cho, C., Reck-Peterson, S.L., Vale, R.D. (2008) Regulatory ATPase sites of cytoplasmic dynein affect processivity and force generation. J Biol Chem 283: 25839-25845. PMID: 18650442. PMCID: PMC2533788.
(pdf) - Douglass, A. and Vale, R.D. (2008) Single-molecule imaging of fluorescent proteins. Methods Cell Biol 85: 113-25. PMID: 18155461.
(pdf) - Goshima, G., Mayer, M., Zhang, N., Stuurman, N. and Vale, R.D. (2008). Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J Cell Biol 181: 421-429. PMID 18443220. PMCID: PMC2364697.
(pdf) - Guo, Y., Walther, T.C., Rao, M., Stuurman, N., Goshima, G.,Terayama, K., Wong, J.S., Vale, R.D., Walter, P. and Farese, R.V. (2008) Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature 453: 657-61. PMID: 18408709. PMCID: PMC2734507.
(pdf) - Roll-Mecak, A. and Vale, R.D. (2008) Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature 451: 363 –- 367. PMID: 18202664. NIHMSID: 208365.
(pdf) - Trammel, M.A., Mahoney, N.M., Agard, D.A. and Vale, R.D. (2008) Mob4 Plays a role in spindle focusing in Drosophila S2 cells. J Cell Sci 121: 1284-1292. PMID: 18388316. NIHMSID: 181554.
(pdf) - Vale, R.D. (2008) Microscopes for fluorimeters: The era of single molecule measurements. Cell 135: 779-785. Supplemental Material. PMID: 19041739. PMCID: PMC2762818.
(pdf) - Yildiz, A., Tomishige, M., Gennerich, A., Vale, R.D. (2008) Intramolecular strain coordinates kinesin stepping behavior along microtubules. Cell 134: 1030-1041. PMID: 18805095. PMCID: PMC2613771.

2007

(pdf) - Dustin, M.L., Starr, T., Coombs, D., Majeau, G.R., Meier, W., Hochman, P.S., Douglass, A., Vale, R.D., Goldstein, B. and Whitty, A. (2007) Quantification and modeling of tripartite CD2-, CD58FC Chimera (Alefacept)-, and CD16-mediated Cell Adhesion. J Biol Chem 282: 34748-34757. PMID: 17911103.______________
(pdf) - Gennerich, A., Carter, A.P., Reck-Peterson, S.L. and Vale, R.D. (2007) Force-induced bidirectional stepping of cytoplasmic Dynein. Cell 131: 952-965. PMID: 18045537. NIHMSID 184966.
(pdf) - Goshima, G., Wollman, R., Goodwin, S., Zhang, N., Scholey, J.M., Vale, R.D. and Stuurman, N. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-421.(Supplemental) PMID: 17412918. NIHMSID: 181537.
(pdf) - Griffis, E.R., Stuurman, N. and Vale, R.D. (2007) Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. J Cell Biol 177: 1005-1015. (cover). PMID: 17576797. PMCID: PMC2064361.
(pdf) - Kaizuka, Y., Douglass, A.,Varma, R., Dustin, M. and Vale, R.D. (2007) Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cell, Proc Natl Acad Sci USA 104: 20296-20301. PMID: 18077330. PMCID: PMC2154425.
(pdf) - Mori, T., Vale, R.D. and Tomishige, M. (2007) How kinesin waits between steps. Nature 450: 750-755. PMID: 18004302.______________
(pdf) - Slep, K.C. and Vale, R.D. (2007) Structural basis of microtubule plus end tracking by XMAP215, Clip-170 and EB1. Mol Cell 27: 976-991. PMID: 17889670. PMCID: PMC2052927.
(pdf) - Stuurman, N., Amodaj, N. and Vale, R.D. (2007) µManager: Open Source software for light microscope imaging. Microscopy Today 15: 42-43. _________

2006

(pdf) - Imanishi, M., Endres, N.F., Gennerich, A., and R.D. Vale (2006) Autoinhibition regulates the motility of the C-elegans intraflagellar transport motor OSM-3. J Cell Biol 174: 931-937. PMID: 17000874; PMCID: PMC2064385.
(pdf) - Endres, N.F., Yoshioka, C., Milligan, R.A. and R. D. Vale. (2006) A lever arm rotation drives motility of the minus-end-directed kinesin, Ncd. Nature 439: 875-878. PMID: 16382238. NIHMSID 184981.
(pdf) - Mahoney, N.M., Goshima, G., Douglass, A.D., Vale, R.D. (2006) Making microtubules and mitotic spindles in cells without functional centrosomes. Curr Biol 16: 564-569. PMID: 16546079. _________
(pdf) - Pan, X.Y., Ou, G.S., Civelekoglu-Scholey, G., Blacque, O.E., Endres, N.F., Tao, L., Mogilner, A., Leroux, M.R., Vale, R.D.,and J M. Scholey (2006) Mechanism of transport of IFT particles in C-elegans cilia by the concerted action of kinesin-II and OSM-3 motors. J Cell Biol 174: 1035-1045. PMID: 17000880; PMCID: PMC2064394.
(pdf) - Reck-Peterson, S.L., Yildiz, A., Carter, A.P., Gennerich, A., Zhang, N., and Vale, R.D. (2006) Single molecule analysis of dynein processivity and stepping behavior. Cell 126: 335-348. PMID: 16873064. NIHMSID 184979.
(pdf) - Roll-Mecak, A. and Vale, R.D. (2006) Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays? J Cell Biol 175: 849-851. PMID: 17178905. PMCID: PMC2064694.
(pdf) - Tomishige, M., Stuurman, N. and R Vale (2006) Single-molecule observations of neck linker conformational changes in the kinesin motor protein. Nat Struct Molec Biol 13: 887-894. PMID: 17013387. ___________________

2005

(pdf) - Cheng, L.W., Viala, J.P.M., Stuurman, N., Weidemann, U., Vale, R.D., Portnoy, D.A. (2005) Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. Proc Natl Acad Sci USA 102: 13646-13651. PMID: 16157870; PMCID: PMC1224656.
(pdf) - Dean, S.O., Rogers, S.L, Stuurman, N., Vale, R.D., and Spudich, James A. (2005) Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc Natl Acad Sci USA 102: 13473-13478. PMID: 16174742; PMCID: PMC1200093.
(abstract) - Douglass, A.D. and Vale R.D. (2005). Single molecule imaging in living cells by total internal reflection fluorescence microscopy. In: Cell Biology: A Laboratory Handbook, 3rd ed., Elsevier Sci (USA), pp. 129-136.
(pdf) - Douglass, A.D. and Vale, R.D. (2005) Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 121: 937-950. (cover). PMID: 15960980. NIHMSID 184810.
(pdf) - Dzhindzhev N.S., Rogers, S.L., Vale R.D., Ohkura H. (2005) Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends. J Cell Sci 118: 3781-3790. PMID: 16105886. ____________________
(pdf) - Gibbons, I.R., Garbarino, J.E., Tan, C.E., Reck-Peterson, S.L., Vale, R.D., and Carter, A.P. (2005) The affinity of the dynein microtubule-binding domain is modulated by the conformation of its coiled-coil stalk. J Biol Chem 280: 23960-23965. PMID: 15826937. PMCID: PMC1464088.
(pdf) - Goshima, G., Nédélec, F., and Vale, R.D. (2005) Mechanisms for focusing mitotic spindle poles by minus-end-directed motor proteins. J Cell Biol 171: 229-240. (cover) PMID: 16247025. PMCID: PMC2171195.
(pdf) - Goshima, G. and Vale, R.D. (2005) Cell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cells. Mol Biol Cell 16: 3896-3907. PMID: 15958489. PMCID: PMC1182325.
(pdf) - Goshima, G., Wollman, R., Stuurman, N., Scholey, J.M., Vale, R.D. (2005) Length control of the metaphase spindle. Curr Biol 15: 1979-1988. (cover) PMID: 16303556. __________________
(pdf) - Jambhekar, A., McDermott, K., Sorber, K, Shepard, K.A., Vale, R.D., Takizawa, P.A., DeRisi, J.L. (2005) Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud-localization in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 102: 18005-18010. PMID: 16326802; PMCID: PMC1298916.
(pdf) - Mennella, V., Rogers, G.C., Rogers, S.L., Buster, D.W., Vale, R.D. and Sharp, D.J. (2005) Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. Nat Cell Biol 7: 235-245. PMID: 15723056.____________________
(pdf) - Roll-Mecak, A. and Vale, R.D. (2005) The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules. Curr Biol 15: 650-655. PMID: 15823537. _____________________
(pdf) - Slep, K.C., Rogers, S.L., Elliott, S.L., Ohkura, H., Kolodziej, P.A. and Vale, R.D. (2005) Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end. J Cell Biol 168: 587-598. PMID: 15699215; PMCID: PMC2171753.

2004

(pdf) - Collins, S.R., Douglass, A.D., Vale, R.D. and Weissman, J.S. (2004) Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLOS Biology 2: 1582-1590 (cover). PMID: 15383837. PMCID: PMC517824.
(pdf) - Dell, K.R. and Vale, R.D. (2004) A tribute to Shinya Inoue and innovation in light microscopy. J Cell Biol 165: 21-5. PMID: 15317131. PMCID: PMC2172095.
(pdf)- Klopfenstein, D.R. and Vale, R.D. (2004) The lipid binding pleckstrin homology in UNC-104 kinesin is necessary for synaptic vesicle transport in the Caenorhabditis elegans. Mol Biol Cell 15: 3729-3739. (online Cover image for MBC 16, January, 2005; MBC Cover) PMID: 15155810; PMCID: PMC491832.
(pdf) - Lawrence C.J., Dawe R.K., Christie K.R., Cleveland D.W., Dawson S.C., Endow S.A., Goldstein L.S., Goodson H.V., Hirokawa N., Howard J., Malmberg R.L., McIntosh J.R., Miki H., Mitchison, T.J. , Okada Y., Reddy A.S., Saxton W.M., Schliwa M., Scholey J.M., Vale R.D., Walczak C.E., Wordeman L. (2004) A standardized kinesin nomenclature. J Cell Biol 167: 19-22. PMID: 15479732. PMCID: PMC2041940.
(pdf) - Reck-Peterson, S.L. and Vale, R.D. (2004) Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 101: 1491-1495. PMID: 14755060; PMCID: PMC341754. Also see: PNAS retraction (pdf).
(pdf) - Rogers, G.C., Rogers, S.L., Schwimmer, T.A., Ems-McClung, S.C., Walczak, C.E., Vale, R.D., Scholey, J.M. and Sharp, D.J. (2004) Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature 427: 364-370. PMID: 14681690.
(pdf) - Rogers, S.L., Weidemann, U., Haecker, U. and Vale, R.D. (2004) Drosophila DRhoGEF2 associates with microtubule plus ends in an EB1-dependent manner. Curr Biol 14: 1827-1833 (cover). PMID: 15498490.
(pdf) - Yildiz, A., Tomishige, M., Vale, R.D. and Selvin, P.R. (2004) Kinesin Walks Hand-Over-Hand. Science 303: 676-678. PMID: 14684828.

2003

(pdf) - Al-Bassam, J., Cui, Y., Klopfenstein, D., Carragher, B.O., Vale, R.D. and Milligan, R. A. (2003) Distinct conformations of the kinesin Unc104 neck regulate a monomer-to-dimer motor transition. J Cell Biol 163: 743-753. PMID: 14638858. PMCID: PMC2173678.
(pdf) - Goshima, G. and Vale, R.D. (2003) The roles of microtubule-based motor proteins in mitosis: Comprehensive RNAi analysis in the Drosophila S2 cell line. J Cell Biol 162: 1003-1016. (figures)(movies)(cover) PMID: 12975346. PMCID: PMC2172859.
(pdf) - Naber N, Rice, S., Matuska M, Vale RD, Cooke R., Pate E. (2003) EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain. Biophys J 84:3190-6. PMID: 12719248. PMCID: PMC1302879.
(pdf) - Naber N., Minehardt T.J., Rice, S., Chen X., Grammer J., Matuska M., Vale R.D., Kollman P.A., Car R., Yount R.G., Cooke R., Pate E. (2003) Closing of the nucleotide pocket of kinesin-family motors upon binding to microtubules. Science 300:798-801. PMID: 12730601.
(pdf) - Rice, S., Cui, Y., Sindelar, C., Naber, N., Matuska M., Vale, R. and Cooke R. (2003) Thermodynamic properties of the kinesin neck region docking to the catalytic core. Biophysical J 84:1844-1854. PMID: 12609886. PMCID: PMC1302753.
(pdf) - Rogers, S.L., Weidemann, U., Stuurman, N. & Vale, R.D. (2003) Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J Cell Biol 162: 1079-1088 (cover). PMID: 12975351. PMCID: PMC2172842.
(pdf) - Rothenberg, M.E., Rogers, S.L., Vale, R.D., Jan, L.Y. and Jan, Y.N. (2003) Drosophila Pod-1 crosslinks both actin and microtubules, and controls the targeting of axons. Neuron 39: 779-791. PMID: 12948445.
(pdf) - Shepard, K.A., Gerber, A.P., Jambhekar, A., Takizawa, P.A., Brown, P.O., Herschlag, D., DeRisi, J.L. and Vale, R.D.. (2003) Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis. Proc Natl Acad Sci USA 100: 11429-11434. (supplemental) PMID: 13679573; PMCID: PMC208774.
(pdf) - Vale, R.D. (2003) Myosin V motor proteins: marching stepwise towards a mechanims. J Cell Biol 163: 445-450 (cover). PMID: 14610051.
(pdf) - Vale, R.D. (2003) The molecular motor toolbox for intracellular transport. Cell 112: 467-480. PMID: 12600311.
(pdf) - Yaffe, M.P., Stuurman, N., Vale, R.D. (2003) Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles. Proc Natl Acad Sci USA 100: 11424-11428. PMID: 12972644; PMCID: PMC208773.

2002

(pdf) - Irie, K., Tadauchi, T., Takizawa, P.A.., Vale, R.D., Matsumoto, K. and Herskowitz, H. (2002) The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast. EMBO J. 21: 1158-1167. PMID: 11867544.
(pdf)- Klopfenstein, D., Holleran, E.A. and Vale, R.D. (2002) Kinesin motors and microtubule- based organelle transport in Dictyostelium discoideum. J Mus Res Cell Motil 23: 631-638. PMID: 12952062.
(pdf) - Klopfenstein, D., Tomishige, M., Stuurman, N. and Vale, R.D. (2002) Role of Phosphatidylinositol(4,5)bisphosphate Organization in Membrane Transport by the Unc104 Kinesin Motor. Cell 109: 347-358 (cover). PMID: 12015984. NIHMSID 184989.
(pdf) - Rogers, S.L., Rogers, G.C., Sharp, D.J. and Vale, R.D. (2002) Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. J Cell Biol 158: 873-884 (cover). PMID: 12213835. PMCID: PMC2173155.
(pdf) - Tomishige, M., Klopfenstein, D., and Vale, R.D. (2002) Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization. Science 297: 2263-2267. PMID: 12351789.

2000

(pdf) - Case, R. B., Rice, S., Hart, C., Ly, B., and Vale, R.D. (2000) Role of the kinesin neck linker and catalytic core in microtubule-based motility. Curr Biol 10: 157- 160 (cover). PMID: 13679573.
(pdf) - Dell, K., Turck, C. W., and Vale, R. D. (2000) Mitotic phosphorylation of the dynein light intermediate chain is mediated by cdc2 kinase. Traffic 1: 38-44. PMID: 11208058.
(pdf) - Govindan, B. and Vale, R. D. (2000) Characterization of a microtubule assembly inhibitor from Xenopus oocytes. Cell Motil Cytoskel 45: 51-57. PMID: 10618166.
(pdf) - Hopkins, S.C., Vale, R.D., and Kuntz, I.D. (2000) Inhibitors of kinesin activity from structure-based computer screening. Biochemistry 39: 2805-2814. PMID: 10704233.
(pdf) - Khan, S., Pierce, D.W., and Vale, R. D. (2000) Interactions of the chemotaxis signal protein CheY with bacterial flagellar motors visualized by evanescent wave microscopy. Curr Biol 10: 927-930. PMID: 10959841.
(pdf) - Klopfenstein, D., Vale, R.D., and Rogers, S. (2000) Motor protein receptors: moonlighting on other jobs. Cell 103: 537-540. PMID: 11106727.
(pdf) - Prahlad, V., Helfand, B.T., Langford, G. M., Vale, R. D., and Goldman, R. D. (2000) Fast transport of neurofilament protein along microtubules in squid axoplasm. J Cell Sci 113: 3939-3946. PMID: 11058081.
(pdf) - Shimizu, T., Thorn, K., Ruby, A. and Vale, R.D. (2000) ATPase kinetic characterization and single molecule behavior of mutant human kinesin motors defective in microtubule-based motility. Biochemistry 37: 5265-5273. PMID: 10819995.
(pdf) - Takizawa, P.A., DeRisi, J.L., Wilhelm, J. E., and Vale, R. D. (2000) Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science 290: 341-344. PMID: 11030653.
(pdf) - Takizawa, P.A. and Vale, R.D. (2000) The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. Proc Natl Acad Sci USA 97: 5273-5278. PMID: 10792032. PMCID: PMC25818.
(abstract) - Thorn, K.S., Naber, N., Matuska, M., Vale, R.D. and Cooke R. (2000) A novel method of affinity-purifying proteins using a bis-arsenical fluorescein. Protein Sci 9: 213-217. PMID: 10716173. PMCID: PMC2144555.
(pdf) - Thorn, K.S., Ubersax, J.A., and Vale, R.D. (2000) Engineering the processive run length of the kinesin motor. J Cell Biol 151: 1093-1100 (cover). PMID: 11086010. PMCID: PMC2174356.
(pdf) - Tomishige, M. and Vale, R.D. (2000) Controlling kinesin by reversible disulfide cross-linking: identifying the motility-producing conformational change. J Cell Biol 151: 1081-1092 (cover). PMID: 11086009. PMCID: PMC2174365.
(pdf) - Vale, R.D. (2000) AAA Proteins: Lords of the ring. J Cell Biol 150: F13-F19. PMID: 10893253. PMCID: PMC2185557.
(abstract) - Vale, R. D., Case, R. B., Sablin, E., Hart, C. and Fletterick, R. (2000) Searching for kinesin's mechanical amplifier. Proc Royal Soc London 355: 449-457. PMID: 10836498. PMCID: PMC1692751.
(pdf) - Vale, R. D. and Milligan, R. D. (2000). The way things move: looking under the hood of molecular motors. Science 288: 88-95. PMID: 10753125.
(pdf) - Wilhelm, J. E., Mansfield, J., Hom-Booher, N., Wang, S., Turck, C., Hazelrigg, T. and Vale, R. D. (2000) Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes. J Cell Biol 148: 427-439. PMID: 10662770. PMCID: PMC2174796.
(pdf) - Wilhelm, J. E., Vale, R.D. and Hedge, R.S. (2000) Coordinate control of translation and localization of Vg1 mRNA in Xenopus oocytes. Proc Natl Acad Sci USA 97: 13132-13137. PMID: 11087864. PMCID: PMC27190.

1999

(pdf) - Friedman, D. S. and Vale, R. D. (1999) Single molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain. Nature Cell Biol. 1: 293-297. PMID: 10559942.
(pdf) - Hartman, James J. and Vale, R. D. (1999) Microtubule disassembly by ATP-dependent oligomerization of the AAA enzyme katanin. Science 286: 782-785. PMID: 10531065.
(pdf) - Pierce, D.W., Hom-Booher, N., Otsuka, A.J. and Vale, R.D. (1999) Single-molecule behavior of monomeric and heteromeric kinesins. Biochem 38: 5412-5421. PMID: 10220328.
(abstract) - Pierce, D.W. and Vale, R.D. (1999) Single molecule fluorescence detection of green fluorescence protein and application to single protein dynamics. Meth Cell Biol 58: 49-73. PMID: 9891374.
(pdf) - Pollock, N., de Hostos, E.L., Turck, C.W. and Vale, R.D. (1999) Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium. J Cell Biol 147: 493-505 (cover). PMID: 10545495.
(pdf) - Rice, S., Lin, A., W., Safer, D., Hart, C. L., Naber, N., Carragher, B. O., Cain, S. M., Pechatnikova, E., Wilson-Kubelek, E. M., Whitaker, M., Pate, E., Cooke R. , Taylor, E. W., Milligan, R. A., and Vale, R. D. (1999) A structural change in the kinesin motor protein that drives motility. Nature 402: 778-783. PMID: 10617199.
(pdf) - Sharp, D.J., McDonald, K.L., Brown, H.M., Matthies, H.J., Walczak, C., Vale, R.D, Mitchison, T.J. and Scholey, J.M. (1999) The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. J Cell Biol 144: 125-138. PMID: 9885249.
(pdf) - Vale, R. D. (1999) Millennial musings on molecular motors. Trends Cell Biol. 9: M38-M42. PMID: 10611679.

1998

(pdf) - de Hostos, E.L., McCaffrey, G., Sucgang, R., Pierce, D.W., and Vale, R. D. (1998) A developmentally regulated kinesin-related motor protein from Dictyostelium discoideum. Mol Biol Cell 9: 2093-2106 (cover). PMID: 9693369.
(pdf) DePace, A.H., Santoso, A., Hillner, P. and Weissman, J.S. (1998) A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell 93: 1241-1252. PMID: 9657156.
(pdf) Hartman, James J., Mahr, Jeff, McNally, Karen, Okawa, Katsuya, Iwamatsu, Akihiro, Thomas, Susan, Cheesman, Sarah, Jeuser, John, Vale, Ronald D. and McNally, Francis J. (1998) Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit. Cell 93: 277-287. PMID: 9568719.
(pdf) - Kull, F. J., Vale, R.D. and Fletterick, R. (1998) The case for a common ancestor: kinesin and myosin motor proteins and G proteins. J Muscle Res Cell Motil 19: 877-886. PMID: 10047987.
(pdf) Lohman, Timothy M., Thorn, Kurt and Vale, Ronald D. (1998) Staying on track: common features of DNA helicases and microtubule motors. Cell 93: 9-12. PMID: 9546385.
(abstract) - Pierce, D.W. and Vale, R.D. (1998) Assaying processive movement of kinesin by fluorescence microscopy. Meth Enzymol 298: 154-171. PMID: 9751879.
(pdf) - Pollock, N., Koonce, M.P., de Hostos, E.L. and Vale, R.D. (1998) In vitro microtubule-based organelle transport in wild-type Dictyostelium and and cells overexpressing a truncated dynein heavy chain. Cell Motil Cytoskel 40: 304-314. PMID: 9678672.
(pdf) - Prahlad, V., Moir, R.D., Vale, R.D. and Goldman, R.D. (1998) Rapid movements of vimentin on microtubule tracks: Kinesin-dependent assembly of intermediate filamenet networks. J Cell Biol 143: 159-170. PMID: 9763428.
(pdf) - Romberg, Laura, Pierce, Daniel W., and Vale, Ronald D. (1998) Role of the kinesin neck region in processive microtubule-based motility. J Cell Biol 140: 1407-1416 (cover). PMID: 9508773.
(pdf) - Sablin E.P., Case R.B., Dai S.C., Hart C.L., Ruby A., Vale R.D. and Fletterick, R. (1998) Direction determination in the minus-end-directed kinesin motor ncd. Nature 395: 813-816. PMID: 9796817.
Wells, S.E., Hillner, P.E., Vale, R.D. and Sachs, A.B. (1998) Circularization of mRNA by eukaryotic translation initiation factors. Mol Cell 2: 135-140. PMID: 9702200.

1997

(pdf) - Case, Ryan B., Pierce, Daniel W., Hom-Booher, Nora; Hart, Cynthia L. and Vale, Ronald D. (1997) The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain. Cell 90: 959-966. PMID: 9298907.
(pdf) - Coppin, Chris M, Pierce, Daniel W., Hsu, Long and Vale, Ronald D. (1997) The load dependence of kinesin's mechanical cycle. Proc Natl Acad Sci USA 94: 8539-44. PMID: 9238012.
(pdf) - Funatsu, Takashi, Harada, Yoshie, Higuchi, Hideo, Tokunaga, Makio, Saito, Kiwamu, Ishii, Yoshiharu, Vale, Ronald D. and Yanagida, Toshio. (1997) Imaging and nano-manipulation of single biomolecules. Biophys Chem 68: 63-72. PMID: 9468610.
(pdf) - Pierce, Daniel W., Hom-Booher, Nora and Vale, Ronald D. (1997) Imaging individual green fluorescent proteins. Nature 388: 338. PMID: 9237750.
(pdf) Sosa, Hernando, Dias, D. Prabha, Hoenger, Andreas, Whittaker, Michael, Wilson-Kubalek, Elizabeth, Sablin, Elena, Fletterick, R., Vale, Ronald D and Milligan, Ronald A. (1997) A model for the microtubule-Ncd motor protein complex obtained by cryo-electron microscopy and image analysis. Cell 90: 217-224. PMID: 9244296.
(pdf) - Takizawa, Peter A., Sil, Anita, Swedlow, Jason R., Herskowitz, Ira and Vale, Ronald D. (1997) Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature 389: 90-93. PMID: 9288973.
(pdf) - Tripet, Brian, Vale, Ronald D. and Hodges, Robert S. (1997) Demonstration of coiled-coil interactions within the kinesin neck region using synthetic peptides. J Biol Chem 272: 8946-56. PMID: 9083016.
(pdf) - Vale, Ronald D. and Fletterick, R. (1997) The design plan of kinesin motors. Annu Rev Cell Dev Biol 13: 745-77. PMID: 9442886.
(pdf) Woehlke, Günther, Ruby, Aaron K., Hart, Cynthia L., Ly, Bernice, Hom-Booher, Nora and Vale, Ronald D. (1997) Microtubule interaction site of the kinesin motor. Cell 90: 207-216. PMID: 9244295.

1996

(pdf) - Coppin, Chris M., Finer, Jeffrey T., Spudich, James A. and Vale, Ronald D. (1996) Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. Proc Natl Acad Sci USA 93: 1913-17. PMID: 8700858.
(pdf) - Fowler, V.M. and Vale, R.D. (1996) Editorial overview: Cytoskeleton. Curr Opinion in Cell Biol 8: 1-3. PMID: 8791412.
(pdf) - Kull, F. Jon, Sablin, Elena P., Lau, Rebecca, Fletterick, R. and Vale, Ronald D. (1996) Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature 380: 550-555 (cover). PMID: 8606779. NIHMSID 184991.
(pdf) - McNally, Francis J., Okawa, K, Iwamatsu, Akihiro and Vale, Ronald D. (1996) Katanin, the microtubule-severing ATPase, is concentrated in centrosomes. J Cell Sci 109: 561-7. PMID: 8907702.
(abstract) - Niclas, J,, Allan, Viki J. and Vale, Ronald D. (1996) Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport. J Cell Biol 133(3): 585-93. PMID: 8636233.
(pdf) - Sablin, Elena P., Kull, F. Jon, Cooke R., Vale, Ronald D. and Fletterick, R. (1996) Crystal structure of the motor domain of the kinesin-related motor ncd. Nature 380: 555-559 (cover). PMID: 8606780.
(pdf) - Vale, Ronald D. (1996) Switches, latches and amplifiers: common themes of G proteins and molecular motors (Commentary). J Cell Biol 135: 291-302. PMID: 8896589.
(pdf) - Vale, Ronald D., Funatsu, Takashi, Pierce, Daniel W., Romberg, Laura, Harada, Yoshie and Yanagida, Toshio. (1996) Direct observation of single kinesin molecules moving along microtubules. Nature 380: 451-453 (cover). PMID: 8602245.
(pdf) - Vale, Ronald D., Reese, T.S. and Sheetz, M.P. (1985) Identification of a novel force generating protein, kinesin, involved in microtubule-based motility. Cell 42: 39-50. NIHMSID 184995.
(abstract) - Vignali, G., Niclas, J., Sprocati, M.T., Vale, R.D., Sirtori, C. and Navone, F. (1996) Differential expression of ubiquitous and neuronal kinesin heavy chains during differentiation of human neuroblastoma and PC12 cells. Eur J Neurosci 8: 536-44. PMID: 8963445.
(abstract) - Wilhelm, James E. and Vale, Ronald D. (1996) A one-hybrid system for detecting RNA-protein interactions. Genes to Cells 1: 317-23. PMID: 9133665.

Reviews & Chapters

(pdf) - Vale RD, Dell K. (2009) The biological sciences in India: Aiming high for the future. J Cell Biol 184: 342-53. (cover) PMID: 19204144. PMCID: PMC2646550.
(pdf) - Vale, R.D. (2008) Microscopes for Fluorimeters: The Era of Single Molecule Measurements . Cell 135: 779-785.
(abstract) - Douglass, A.D. and Vale R.D. (2005). Single molecule imaging in living cells by total internal reflection fluorescence microscopy. In: Cell Biology: A Laboratory Handbook, 3rd ed., Elsevier Sci (USA), pp. 129-136.
(pdf) - Klopfenstein, D., Vale, R.D., and Rogers, S. (2000) Motor protein receptors: moonlighting on other jobs. Cell 103: 537-540.
(pdf) Vale, R.D. (2000) AAA Proteins: Lords of the ring. J Cell Biol 150: F13-F19
(abstract) Vale, R. D., Case, R. B., Sablin, E., Hart, C. and Fletterick, R. (2000) Searching for kinesin's mechanical amplifier. Proc Royal Soc London 355: 449-457.
(pdf) - Vale, R.D., Milligan, R.A. (2000) The way things move: looking under the hood of molecular motor proteins. Science 288: 88-95
(pdf) - Vale, R. D. (1999) Millennial musings on molecular motors. Trends Cell Biol 9: M38-M42.
(abstract) - Pierce, D.W. and Vale, R.D. (1998) Detection of single molecule GFP fluorescence. Meth Enzymol 298: 154-171
(pdf) - Vale, Ronald D. and Fletterick, R. (1997) The design plan of kinesin motors. Annu Rev Cell Dev Biol 13: 745-77.
(pdf) - Vale, R.D., Reese, T.S. and Sheetz, M.P. (1985) Identification of a novel force generating protein, kinesin, involved in microtubule-based motility. Cell 42: 39-50. NIHMSID 184995.
(pdf)- Vale, Ronald D. (1996) Switches, latches and amplifiers: common themes of G proteins and molecular motors (Commentary). J Cell Biol 135: 291-302

Publications pre-1995

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